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Vitola: Pyramid Size: 4 1/2 x 52 Approximate Smoking Time: 3045 minutes Strength: Medium Wrapper: Maduro Tasting Notes: Sweet aromatic profile with cocoa and coffee notes Hints of dried fruit, vanilla, and light spice Rich, smooth smoke with a dessert-like finish Best Pairings: Spiced rum, mocha latte, chocolate truffles Highlight: A bold, flavorful smoke from Drew Estates Deadwood line, infused with signature aromatic sweetness The Crazy Alice offers a unique twist on short-format cigars with its pyramid shape, maduro wrapper, and unmistakable Deadwood flair

Overexpression of miR-34a-5p has been found to be able to mitigate liver fibrosis development and progression by targeting Smad 4 in HSCs (Zheng et al., 2022)

The FOOTNOTES video was produced by Richie Bozek

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Nicotine is a mind-altering stimulant, having a lasting effect on human neurochemistry